Food Study Reference: Thompson, L. U., Boucher, B. A., Liu, Z., Cotterchio, M., and Kreiger, N. (2006) Phytoestrogen content of foods consumed in Canada, including isoflavones, lignans, and coumestan. Nutr Cancer 54, 184-201
Baby photo and story from Pediatric AnnalsVol. 41, No. 2
PMID 17267908 Case Reports of 3 boys with gynecomastia after topical application of lavender and tea tree oil products which resolved after stopping products. Funded by NIH.
PMID: 31393563 Case Reports of lavender-fragranced products and breast growth in children, with extensive workup. Supports a possible link with idiopathic prepubertal breast development. Funded by NIH. Authors make a point that case reports and epidemiological studies may be all we ever have on lavender and tea tree oil effects on children because “intentional dosing [of children] with essential-oil components is untenable.” They report that the level of activity of the more active components as reported from their experimental data is similar to that of estriol (a native human estrogen).
PMID 32147050 A literature review claiming no estrogenic effect published by authors all from Franklin School of Integrative Health Sciences – Research arm: Franklin Health Research (franklinhealth.org), which according to their website provide clinical research services for the natural products industry, serving the following markets: Consumer Brands, Ingredient Suppliers, Drug Development.
Marijuana Smoking and Gynecomastia
PMID 36378033 Just released retrospective case-controlled study of chest CT findings in marijuana smokers indicating gynecomastia in marijuana smokers at 38%. Significantly higher than control group (16%0 and tobacco-only smokers (11%).
PMID 16499939, 16392670 Studies showed that marijuana smoke condensate was estrogenic whereas the major cannabinoid components, THC, CBD, and CBN were not.
Credit The Estrogenic Top Ten List to Anthony Jay, PhD, and his book, Estrogeneration, How Estrogenics are Making You Fat, Sick, and Infertile, 2017, p18-19.
Myers SL, Yang CZ, Bittner GD, Witt KL, Tice RR, Baird DD. Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products. J Expo Sci Environ Epidemiol. 2015 May;25(3):271-7. doi: 10.1038/jes.2014.32. Epub 2014 May 21. PMID: 24849798; PMCID: PMC4318791.